I've got a Virus TI and Nord Lead 3 right now and can mostly echo the other sentiments in this thread:
Virus Pros:
1. Pretty flexible architecture. Analog-style and digital oscillators, good filters.
2. Excellent onboard effects.
3. 16-part multitimbral.
Virus Cons:
1. Darker, murkier, less lively sound.
2. Interface is kind of obtuse. Lots of poking around in menus. TI is better than C but still fiddly.
Nord Pros:
1. Fantastic, bright lively sound.
2. Best interface on any synth ever.
3. Morph system encourages really *playing*.
Nord Cons:
1. No onboard effects.
2. Only 4-part multitimbral.
3. Far fewer modulation options.
All things considered I lean towards the Nord because I prefer it's sound and I *love* the interface. For me the whole point of a hardware synth is the interface and the Virus isn't that great in that respect. I'd probably just use softsynths instead.
Here's a simple track I did recently using just the Nord and some drums:
http://www.caddr.com/music/T.mp3I don't know the Q but from what I've read about it might be a great middle ground in between the Nord and the Virus.